Division of Biology and Medicine
Legorreta Cancer Center

SRMC

As a requirement of NCI designation and a critical facet of the success of our clinical trials program, the Scientific Review & Monitoring Committee analyzes all proposals for clinical trials to provide effective and unique treatment opportunities for Rhode Island cancer patients.

Breadcrumb

SRMC

As a requirement of NCI designation and a critical facet of the success of our clinical trials program, the Scientific Review & Monitoring Committee analyzes all proposals for clinical trials to provide effective and unique treatment opportunities for Rhode Island cancer patients.

Our Protocol Review and Management System is used across our partnered health systems to review clinical trial proposals prior to submission to the Institutional Review Board. Clinical trials are evaluated for scientific merit, methodology and statistical design, institutional priority, and monitor progress of studies, to select the strongest trials that fulfill the vision of our cancer center.

The Committee members hold significant experience and depth of expertise to perform critical and sound scientific review of all cancer-relevant clinical research which prioritizes the needs of our catchment area and community.

Submit to the SRMC

 

SRMC Co-Chairpersons

Full Reviews

  • All Interventional Investigator-Initiated Trials (IITs)
  • New industry, external academic or foundation-sponsored Interventional cancer research studies that have not previously undergone external peer review by one of the NCI approved groups or via a NCI-approved external PRMS.
  • Annual renewal of interventional cancer studies that have not made adequate progress towards accrual goals.

Expedited Reviews

  • NCI-approved National Clinical Trials Network studies.
  • Other trials that have been peer-reviewed by one of the NCI approved groups or via a NCI-approved external PRMS. 
  • Rare Disease Studies

Committee Decisions

  • Approval: Full approval is given and the PI is notified. 
  • Approval with Stipulations: the study is scientifically sound and acceptable if minor clarifications are provided. 
  • Tabled: The study must be re-submitted in its entirety to the SRMC for full-board review with significant modifications and responses to the questions raised by the SRMC during its initial review. 
  • Disapproved: The study is neither scientifically sound nor ethical.